HEPATIBEN – Supporting Research

Hepatiben is our main liver cleansing supplement with half the ingredients dedicated to liver cleanse and the other to leaky gut repair. The following are research papers supporting their use.

• Silybin combined with Phosphatidylcholine and Vitamin E in patients with nonalcoholic fatty liver disease: a randomized controlled trial. Free Radical Biology & Medicine Journal, Feb 2012
• Is Silymarin Hepatoprotective in Alcoholic Liver Disease? https://journals.lww.com/
• Non-Alcoholic Fatty Liver Disease (NAFLD) Nutritional and Supplemental Support. Life Extension
• Effect of Silybin on high-fat-induced fatty liver in rats: Silybin, Vitamin E. Brazil Journal of Medical Biology. July, 2011
• The effect of a Silybin, Vitamin E, Phospholipid complex on non alcoholic fatty liver disease. Digestive Disease & Sciences. April, 2007.
• Co-Delivery system: Silybin enhances bioavailability of Curcumin by 3.5 fold. Drug Liver Translational Research. Aug, 2015.
• A Placebo-Controlled Trial of Silymarin in Patients with NAFLD. https://hepatmon.com/?page=article&article_id=479
• The Efficacy of Silymarin in Decreasing Transaminase Activities in NAFLD Caspian Journal Of Internal Medicine. Winter, 2014
• N-Acetylcysteine (NAC) Improves Liver Function in Patients with Non-Alcoholic Fatty Liver Disease. Hepatitis Monthly, March 2010
• Glutathione, Berberine. Leaky Gut Syndrome: Breaking The Cycle. Dr. Leo Galland
• Alpha lipoic acid Reduces Oxidative Stress in NAFLD. Journal of Medical Food, Feb, 2014
• Role Methionine–Choline-Deficient Diet In Fatty Liver. El Sevier, July, 2014.

GUT HEALTH – Supporting Research

SERRAPEPTASE

Serrapeptase is primarily used to breakup biofilm and support scar tissue removal in the body. This is helpful not only in gut health applications, but also in such as endometriosis, impacting 1 in 10 women. The following are research papers supporting their use.

• The role of bacterial biofilms in chronic infections. https://www.ncbi.nlm.nih.gov/pubmed/23635385
• Biofilm formation protecting pathogenic candida. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC95423/?report=reader
• Serrapeptase shown to inhibit biofilm. https://www.ncbi.nlm.nih.gov/pubmed/8109925
• Serrapeptase anti-inflammatory properties. https://www.lifeextension.com/Magazine/2003
• Serrapeptase and nattokinase for relieving Alzheimer’s. https://www.ncbi.nlm.nih.gov/pubmed/23821590

CANDIDA COMPLEX

Candida Complex is the most effective way to rebalance candida and return patients to a normal flora. This formula combines multiple ways to attract candida and as a side benefit also removes parasites and other deleterious organisms. The following are research papers supporting their use.

• Oregano Oil Impact on Fluconazole Resistance Candida Fungus. Canadian Journal of Microbiology. Nov, 2008
• Caprylic Acid effective treatment of intractable medical problems including Candida albicans. Acupuncture & Electro-therapeutics Research, 2011
• Caprylate inactivating enveloped virus. Biologicals, June, 2002
• Effects of probiotics on nonalcoholic fatty liver disease. World Journal Gastroenterology. Oct, 2013.
• Zinc and its importance for human health. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3724376/
• Herbal Medicines Used in Digestive Health and Disease, Slippery Elm Bark’s Role. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6065514/
• Slippery Elm’s role in relieving urinary tract inflammation, irritable bowel syndrome (IBS) https://www.researchgate.net/publication/319590405_Slippery_Elm
• Aloe vera Is Effective and Safe Treatment of Irritable Bowel Syndrome https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6175553/
• Health Effects of Grape Seed Extract on the gastrointestinal tract. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7696942/
• Grape Seed Extract Reduces Inflammatory Response and Oxidative Stress Induced in Human Gastric Epithelial Cells. https://pubmed.ncbi.nlm.nih.gov/34208004/
• Favorable effects of grape seed extract on intestinal epithelial differentiation and barrier function. https://pubmed.ncbi.nlm.nih.gov/25990915/
• Wormwood accelerates healing in patients with Crohn’s disease. https://pubmed.ncbi.nlm.nih.gov/19962291/

LEAKY GUT REPAIR

Leaky Gut Repair is critical in healing the gut lining and reducing inflammation. Physicians also find it helpful in addressing ulcers. The following are research papers supporting their use.

• Glutamine and Gut Integrity. Lancet, May, 1993
• Effect of Quercetin and other flavonoids on antigen-induced histamine secretion. Journal of allergy and Immunology. June, 1984
• Zinc supplementation tightens “leaky gut” in Crohn’s disease. https://pubmed.ncbi.nlm.nih.gov/11383597/
• Herbal Medicines Used in Digestive Health and Disease, Slippery Elm Bark’s Role. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6065514/
• Slippery Elm’s role in relieving urinary tract inflammation, irritable bowel syndrome (IBS) https://www.researchgate.net/publication/319590405_Slippery_Elm
• Aloe vera Is Effective and Safe Treatment of Irritable Bowel Syndrome https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6175553/
• N-Acetylglucosamine for Treatment of Inflammatory Bowel Disease. https://www.naturalmedicinejournal.com/journal/2015-04/n-acetylglucosamine-treatment-inflammatory-bowel-disease
• Anti-inflammatory activity of Licorice Root. https://pubmed.ncbi.nlm.nih.gov/27650551/
• Anti-inflammatory effects of methylsulfonylmethane (MSM). https://pubmed.ncbi.nlm.nih.gov/19336900/
• Role of Bromelain in anti-inflammatory and wound healing applications. https://pubmed.ncbi.nlm.nih.gov/27602208/

Digest Harmony

• The role of enzyme supplementation in digestive disorders. https://pubmed.ncbi.nlm.nih.gov/19152478/
• Digestive Enzyme Supplementation in Gastrointestinal Diseases. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4923703/
• Aloe vera Is Effective and Safe Treatment of Irritable Bowel Syndrome https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6175553/

Immune ProPlus

• Immune modulatory effects of Prunella vulgaris (Heal-All Herb). https://pubmed.ncbi.nlm.nih.gov/15702244/
• Success of L-lysine therapy in recurrent herpes simplex. https://pubmed.ncbi.nlm.nih.gov/3115841/
• Lysine for Herpes. https://pubmed.ncbi.nlm.nih.gov/30881246/
• Antibacterial activity of Oregano. https://pubmed.ncbi.nlm.nih.gov/23484421/
• Oregano recognized antimicrobial activity and anti-viral and anti-fungal properties. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152729/
• Olive Leaf Extract exhibits antiviral activity against viral (VHSV). https://pubmed.ncbi.nlm.nih.gov/15869811/
• Olive Leaf Extract significantly reduced recovery time in upper respiratory illness. https://pubmed.ncbi.nlm.nih.gov/30744092/
• Olive Leaf activities include antioxidant, anti-inflammatory, anti-atherogenic, anti-cancer activities, antimicrobial activity, antiviral activity, hypolipidemic and hypoglycemic effect. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3002804/
• Anti-influenza virus effects of Elderberry (European Elder Fruit). https://pubmed.ncbi.nlm.nih.gov/22972323/
• European Elder Fruit for prevention and treatment of viral respiratory illnesses. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8026097/
• Novel antibacterial activity of Monolaurin compared with conventional antibiotics. https://pubmed.ncbi.nlm.nih.gov/17966176/
• Adaptogenic and Anti-Stress Effects of Ashwagandha Root Extract. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6979308/
• Royal Jelly: A Comprehensive Review of Their Anti-viral and Wound Healing Biological Actions. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5549483/

Sugar Balance

• Berberine on blood glucose in patients with type 2 diabetes. https://pubmed.ncbi.nlm.nih.gov/30393248/
• Cinnamon bark in potentially alleviating diabetes through insulin-potentiating activity. https://pubmed.ncbi.nlm.nih.gov/18284204/
• Cinnamon use in type 2 diabetes. https://pubmed.ncbi.nlm.nih.gov/24019277/
• Anti-diabetic effect of Cinnamon Bark Extract on blood glucose. https://pubmed.ncbi.nlm.nih.gov/16213119/
• Gymnema sylvestre for Diabetes: From Traditional Herb to Future’s Therapeutic. https://pubmed.ncbi.nlm.nih.gov/27834124/
• Gymnema sylvestre improves glucose tolerance in vivo and stimulates insulin secretion. https://pubmed.ncbi.nlm.nih.gov/22911568/
• Diabetes and Alpha Lipoic Acid’s multiple mechanisms of improvement. https://pubmed.ncbi.nlm.nih.gov/22125537/
• Alpha-lipoic acid impact on improved insulin sensitivity, oxidative stress, and neuropathy in diabetic patients. https://pubmed.ncbi.nlm.nih.gov/19019027/
• Anti-diabetic effects of Chaga in type 2 diabetic mice. https://pubmed.ncbi.nlm.nih.gov/28954386/
• Cayenne Reduces Blood Glucose by Increasing Insulin Levels and Glycogen Content. https://pubmed.ncbi.nlm.nih.gov/28230360/
• Hypoglycemic effect of Bitter Melon compared with metformin in newly diagnosed type 2 diabetes patients. https://pubmed.ncbi.nlm.nih.gov/21211558/
• Antidiabetic effects of Bitter Melon and its medicinal potency. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4027280/